Dataset | Set_04_DMpreB_versus_WTpreB.phenotype_DMpreB_versus_WTpreB.cls #DMpreB_versus_WTpreB |
Phenotype | phenotype_DMpreB_versus_WTpreB.cls#DMpreB_versus_WTpreB |
Upregulated in class | WTpreB |
GeneSet | NCI_IL12-MEDIATED SIGNALING EVENTS |
Enrichment Score (ES) | -0.688636 |
Normalized Enrichment Score (NES) | -1.7222534 |
Nominal p-value | 0.0 |
FDR q-value | 0.009562945 |
FWER p-Value | 0.068 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | ARRB2 | 20806 | 1172 | 2.927 | -0.0405 | No | ||
2 | MAPK8 | 6459 | 1644 | 2.061 | -0.0500 | No | ||
3 | CD86 | 1660 22601 | 1910 | 1.663 | -0.0514 | No | ||
4 | MALT1 | 6274 | 1985 | 1.573 | -0.0431 | No | ||
5 | RAB7A | 9684 5347 9683 | 2086 | 1.451 | -0.0372 | No | ||
6 | CHUK | 23665 | 2157 | 1.372 | -0.0304 | No | ||
7 | IL12RB1 | 3916 18582 | 2185 | 1.330 | -0.0215 | No | ||
8 | IKBKB | 4907 | 2775 | 0.746 | -0.0475 | No | ||
9 | IL2RB | 22219 | 3089 | 0.502 | -0.0605 | No | ||
10 | IL18R1 | 14263 | 3136 | 0.468 | -0.0593 | No | ||
11 | EOMES | 4669 | 3300 | 0.391 | -0.0651 | No | ||
12 | IL1R1 | 14264 3987 | 3542 | 0.316 | -0.0757 | No | ||
13 | CD3D | 19473 | 3849 | 0.241 | -0.0903 | No | ||
14 | IL1B | 14431 | 3902 | 0.230 | -0.0913 | No | ||
15 | IL6ST | 4920 | 3953 | 0.221 | -0.0923 | No | ||
16 | IL4 | 9174 | 4886 | 0.119 | -0.1417 | No | ||
17 | CD4 | 16999 | 5252 | 0.099 | -0.1607 | No | ||
18 | XPO1 | 4172 | 5363 | 0.093 | -0.1659 | No | ||
19 | FBXW11 | 20926 | 5626 | 0.080 | -0.1794 | No | ||
20 | SRC | 5507 | 5727 | 0.076 | -0.1843 | No | ||
21 | IL27 | 17636 | 7242 | 0.038 | -0.2657 | No | ||
22 | IL12RB2 | 17128 | 7245 | 0.038 | -0.2656 | No | ||
23 | IL13 | 20461 | 7270 | 0.037 | -0.2666 | No | ||
24 | GATA3 | 9004 | 7429 | 0.034 | -0.2748 | No | ||
25 | FRAP1 | 2468 15991 | 7625 | 0.031 | -0.2851 | No | ||
26 | CD3E | 8714 | 8077 | 0.024 | -0.3093 | No | ||
27 | CCL3 | 20317 | 8171 | 0.022 | -0.3142 | No | ||
28 | IL17A | 14289 | 8269 | 0.021 | -0.3192 | No | ||
29 | IL2 | 15354 | 8580 | 0.017 | -0.3359 | No | ||
30 | CD28 | 14239 4092 | 8632 | 0.016 | -0.3385 | No | ||
31 | CD247 | 4498 8715 | 9036 | 0.011 | -0.3602 | No | ||
32 | B2M | 72 14882 | 9089 | 0.011 | -0.3629 | No | ||
33 | ATM | 2976 19115 | 9513 | 0.005 | -0.3857 | No | ||
34 | NFKB2 | 23810 | 9535 | 0.005 | -0.3868 | No | ||
35 | PRF1 | 20011 | 9734 | 0.002 | -0.3975 | No | ||
36 | CCL4 | 1362 20730 | 10317 | -0.005 | -0.4289 | No | ||
37 | IL12B | 20918 | 10475 | -0.007 | -0.4373 | No | ||
38 | CCR5 | 8754 4534 | 10515 | -0.007 | -0.4394 | No | ||
39 | IL6 | 16895 | 10534 | -0.008 | -0.4403 | No | ||
40 | TBX21 | 20276 | 10858 | -0.012 | -0.4576 | No | ||
41 | CD3G | 19139 | 11522 | -0.022 | -0.4933 | No | ||
42 | IKBKG | 2570 2562 4908 | 11885 | -0.028 | -0.5126 | No | ||
43 | GZMA | 21343 | 12107 | -0.032 | -0.5243 | No | ||
44 | IL18RAP | 14262 | 12314 | -0.037 | -0.5351 | No | ||
45 | PIK3R1 | 3170 | 12502 | -0.041 | -0.5449 | No | ||
46 | RIPK2 | 2528 15935 | 12517 | -0.042 | -0.5453 | No | ||
47 | GZMB | 21810 | 12565 | -0.043 | -0.5475 | No | ||
48 | SPHK2 | 1217 1806 12155 | 13302 | -0.065 | -0.5868 | No | ||
49 | PIK3CA | 9562 | 13540 | -0.075 | -0.5990 | No | ||
50 | ATF2 | 4418 2759 | 13664 | -0.081 | -0.6050 | No | ||
51 | TNF | 23004 | 13668 | -0.082 | -0.6046 | No | ||
52 | CD8B | 4502 17418 | 13714 | -0.084 | -0.6063 | No | ||
53 | CD80 | 22758 | 13921 | -0.096 | -0.6167 | No | ||
54 | PIAS2 | 1948 5102 | 14002 | -0.102 | -0.6202 | No | ||
55 | FASLG | 13789 | 14511 | -0.153 | -0.6465 | No | ||
56 | BCL3 | 8654 | 14544 | -0.157 | -0.6470 | No | ||
57 | ERC1 | 1013 17021 995 1136 | 14629 | -0.171 | -0.6502 | No | ||
58 | FOS | 21202 | 14800 | -0.201 | -0.6578 | No | ||
59 | IL2RG | 24096 | 14876 | -0.214 | -0.6602 | No | ||
60 | STAT4 | 14251 9907 | 15027 | -0.245 | -0.6664 | No | ||
61 | STAT6 | 19854 9909 | 15032 | -0.245 | -0.6647 | No | ||
62 | JAK2 | 23893 9197 3706 | 15111 | -0.267 | -0.6669 | No | ||
63 | STAT5A | 20664 | 15113 | -0.268 | -0.6648 | No | ||
64 | LCK | 15746 | 15440 | -0.368 | -0.6796 | No | ||
65 | TNFRSF1A | 1181 10206 | 15447 | -0.370 | -0.6770 | No | ||
66 | IFNG | 19869 | 15478 | -0.380 | -0.6757 | No | ||
67 | UBE2D3 | 7253 | 15487 | -0.387 | -0.6731 | No | ||
68 | EBI3 | 23193 | 15490 | -0.390 | -0.6702 | No | ||
69 | RELB | 17942 | 15595 | -0.439 | -0.6724 | No | ||
70 | IRF1 | 1336 1258 1433 9182 | 15819 | -0.564 | -0.6801 | No | ||
71 | NOD2 | 6384 | 15978 | -0.694 | -0.6832 | Yes | ||
72 | IL27RA | 11949 | 15991 | -0.707 | -0.6784 | Yes | ||
73 | REL | 9716 | 16182 | -0.909 | -0.6816 | Yes | ||
74 | MAPK9 | 1233 20903 1383 | 16314 | -1.011 | -0.6808 | Yes | ||
75 | CYLD | 18532 | 16380 | -1.083 | -0.6759 | Yes | ||
76 | TYK2 | 12058 19215 | 16487 | -1.199 | -0.6723 | Yes | ||
77 | MAP2K3 | 20856 | 16736 | -1.563 | -0.6735 | Yes | ||
78 | JAK1 | 15827 | 16753 | -1.590 | -0.6620 | Yes | ||
79 | RAN | 5356 9691 | 16867 | -1.732 | -0.6546 | Yes | ||
80 | GADD45G | 21637 | 17072 | -2.018 | -0.6500 | Yes | ||
81 | BIRC2 | 4397 4398 | 17074 | -2.019 | -0.6343 | Yes | ||
82 | MAP2K6 | 20614 1414 | 17087 | -2.043 | -0.6191 | Yes | ||
83 | PRKCA | 20174 | 17337 | -2.525 | -0.6129 | Yes | ||
84 | MAPK14 | 23313 | 17421 | -2.682 | -0.5966 | Yes | ||
85 | GADD45B | 19935 | 17545 | -2.955 | -0.5802 | Yes | ||
86 | STAT2 | 19840 | 17576 | -3.019 | -0.5584 | Yes | ||
87 | IL2RA | 4918 | 17622 | -3.145 | -0.5363 | Yes | ||
88 | JUN | 15832 | 17687 | -3.335 | -0.5139 | Yes | ||
89 | TGFB1 | 18332 | 17722 | -3.435 | -0.4890 | Yes | ||
90 | NFKB1 | 15160 | 17789 | -3.591 | -0.4646 | Yes | ||
91 | SOCS1 | 4522 | 17793 | -3.598 | -0.4368 | Yes | ||
92 | MAP3K14 | 11998 | 17837 | -3.699 | -0.4104 | Yes | ||
93 | NFKBIA | 21065 | 17838 | -3.699 | -0.3816 | Yes | ||
94 | ETV5 | 22630 | 17951 | -4.075 | -0.3560 | Yes | ||
95 | RELA | 23783 | 17959 | -4.092 | -0.3246 | Yes | ||
96 | CREBBP | 22682 8783 | 17993 | -4.203 | -0.2937 | Yes | ||
97 | SYK | 21636 | 18074 | -4.548 | -0.2626 | Yes | ||
98 | BCL10 | 15397 | 18081 | -4.569 | -0.2274 | Yes | ||
99 | TRAF6 | 5797 14940 | 18115 | -4.665 | -0.1929 | Yes | ||
100 | TNFAIP3 | 19810 | 18134 | -4.740 | -0.1571 | Yes | ||
101 | IL18 | 9172 | 18223 | -5.139 | -0.1219 | Yes | ||
102 | STAT1 | 3936 5524 | 18294 | -5.505 | -0.0828 | Yes | ||
103 | IL12A | 4913 | 18393 | -6.118 | -0.0406 | Yes | ||
104 | STAT3 | 5525 9906 | 18455 | -6.760 | 0.0087 | Yes |